Bitter Melon Enhances Natural Killer–Mediated Toxicity against Head and Neck Cancer Cells
نویسندگان
چکیده
منابع مشابه
Immunomodulatory role of bitter melon extract in inhibition of head and neck squamous cell carcinoma growth
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer and leading cause of cancer related mortality worldwide. Despite the advancement in treatment procedures the overall survival rate of patients has not considerably enhanced in the past few decades. Therefore, new strategies to achieve a favorable response for the improvement in the prognosis of HNSCC are urgently need...
متن کاملBitter Melon Reduces Head and Neck Squamous Cell Carcinoma Growth by Targeting c-Met Signaling
Head and neck squamous cell carcinoma (HNSCC) remains difficult to treat, and despite of advances in treatment, the overall survival rate has only modestly improved over the past several years. Thus, there is an urgent need for additional therapeutic modalities. We hypothesized that treatment of HNSCC cells with a dietary product such as bitter melon extract (BME) modulates multiple signaling p...
متن کاملBitter melon protects against ER stress in LS174T colonic epithelial cells
BACKGROUND Bitter Melon (BM) has been used as a functional food in traditional Chinese and Indian medicine for many generations and has gained a great deal of attention due to its apparent benefits in moderating some of the pathogenic processes in a variety of inflammatory conditions. BM extract (BME) has been shown to possess strong anti-oxidant properties. In addition, it can ameliorate oxida...
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Quality of life in head and neck cancer patients
متن کاملMethanolic Extracts of Bitter Melon Inhibit Colon Cancer Stem Cells by Affecting Energy Homeostasis and Autophagy
Bitter melon fruit is recommended in ancient Indian and Chinese medicine for prevention/treatment of diabetes. However its effects on cancer progression are not well understood. Here, we have determined the efficacy of methanolic extracts of bitter melon on colon cancer stem and progenitor cells. Both, whole fruit (BMW) and skin (BMSk) extracts showed significant inhibition of cell proliferatio...
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ژورنال
عنوان ژورنال: Cancer Prevention Research
سال: 2017
ISSN: 1940-6207,1940-6215
DOI: 10.1158/1940-6207.capr-17-0046